Targeted drug delivery

Целевая доставка лекарств в клетки
Целевая доставка лекарств в клетки
клетки легочного эпителия, цитоскелет окрашен зеленым маркером, ядра клеток синим

Currently, the effectiveness of most drugs is partially limited by the fact the majority of biologically active compounds affect the body as a whole, and their action is not limited to those cells and tissues for which the drug was intended. It is possible to solve this problem by developing drug delivery systems that can ensure that drug is delivered to the specific area of ​​the body to those cells it is required to affect. Such an approach will not only increase the effectiveness of the treatment but will also mitigate undesirable side effects. This will in turn make it possible to make advantage of potentially highly effective drugs that have not been used in the clinical practice due to poor biodistribution or various adverse effects.

Our research interests include the development of delivery systems aimed at the cancer treatment, gene therapy, systems with controlled drug release, and diagnostic systems for computed tomography and magnetic resonance imaging.

We conduct our research in close collaboration with both Russian research teams: First St. Petersburg State Medical University, Peter the Great St. Petersburg Polytechnic University, and foreign: Hamburg University, Italian Institute of Technology, Tel Aviv University and Queen Mary University of London.

Staff

Целевая доставка лекарств в клетки
Целевая доставка лекарств в клетки
клетки легочного эпителия, цитоскелет окрашен зеленым маркером, ядра клеток синим

Publications

2020

8.
Susana Carregal-Romero
, pp.
227-241
, 2020
[DOI:
10.1007/978-1-0716-0215-7_15
] [ SJR:
0.605
]

2019

5.
Marco Cassani
Markus J Barthel
Helena Gavilan
Niccolò Silvestri
Alberto Escudero
Alice Scarpellini
Federica Lucchesi
Francisco J. Teran
Wolfgang J Parak
Teresa Pellegrino
  , vol.
11
, pp.
41957-41971
, 2019
[DOI:
10.1021/acsami.9b15501
] [ IF:
8.456
, SJR:
2.596
]
4.
Albert R. Muslimov
Alexander S. Timin
Valery R. Bichaykina
Timofey E. Karpov
Aliaksei Dubavik
Jaafar Ghanbaja
Gleb B. Sukhorukov
, vol.
8
, pp.
1137-1147
, 2019
[DOI:
10.1039/c9bm00926d
] [ IF:
5.251
, SJR:
1.539
]
3.
Oleksii O. Peltek
Albert R. Muslimov
Alexander S. Timin
, vol.
17
, pp.
90
, 2019
[DOI:
10.1186/s12951-019-0524-9
] [ IF:
5.345
, SJR:
1.255
]
2.
All-optical nanoscale heating and thermometry with resonant dielectric nanoparticles for photoinduced tumor treatment
Alexander S. Timin
Albert R. Muslimov
Jaafar Ghanbaja
Pintu Ghosh
Qiang Li
, 2019
1.
Alexander S. Timin
Albert R. Muslimov
Timofey E. Karpov
Olga S. Epifanovskaya
Alena I. Shakirova
Yana V. Tarakanchikova
Kirill V. Lepik
Vladislav S. Sergeev
Gleb B. Sukhorukov
Boris V. Afanasyev
  , vol.
11
, pp.
13091-13104
, 2019
[DOI:
10.1021/acsami.8b22685
] [ IF:
8.596
, SJR:
2.596
]