Optical seminar | 30 September 2022

Alkynes and alkenes are widely used to obtain compounds of practical value: monomers for polymerization, nonlinear optics materials, liquid crystals, organic semiconductors and sensors, molecular machines, pharmaceuticals, etc. Alkynes find application in nanotechnology, biology, pharmacology, and medicine.
Here I will discuss possible methods for generating highly reactive cationic sites in organic molecules by the action of Bronsted superacids and strong Lewis acids. Theoretical calculations of possible intermediates and competitive pathways of intra- and intermolecular reactions of superelectrophilic particles in presence of arenes and without them.

Main paper/arXiv, related to the seminar, and other references

1. Boyarskiy V.P., Ryabukhin D.S., Bokach N.A., Vasilyev A.V. ALKENYLATION OF ARENES AND HETEROARENES WITH ALKYNES. Chem. Rev. 2016, 116, 5894−5986.
2. Ryabukhin D.S., Vasilyev A.V. SYNTHESIS OF (iso)QUINOLINE, (iso)COUMARIN AND (iso)CHROMENE DERIVATIVES FROM ACETYLENE COMPOUNDS. Russ. Chem. Rev., 2016, 85 (6) 637 -665
3. Gurskaya L.Yu., Belyanskaya D.S., Ryabukhin D.S., Nilov D.I., Boyarskaya I.A., Vasilyev A.V. REACTIONS OF N,3-DIARYLPROPIOLAMIDES WITH ARENES UNDER SUPERELEC-TROPHILIC ACTIVATION: SYNTHESIS OF 4,4-DIARYL-3,4-DIHYDROQUINOLIN-2(1H)-ONES AND THEIR DERIVATIVES. Beilstein J. Org. Chem. 2016, 12, 950–956.
4. Kalyaev M.V., Ryabukhin D.S., Borisova M.A., Ivanov A.Yu., Boyarskaya I.A., Borovkova K.E., Nikiforova L.R., Salmova J.V., Ul’yanovskii N.V., Kosyakov D.S., Vasilyev A.V. Synthesis of 3-Aryl-3-(Furan-2-yl)Propanoic Acid Derivatives, and Study of Their Antimicrobial Activity. Mole-cules 2022, 27(14), 4612.